Rare disease is anything but rare. As many as 7,000 rare diseases affect 400 million people globally. The vast majority are not well understood, and less than 5% have approved treatments. Yet worldwide, patients and their loved ones are meeting these challenges head on. They are going back to school to become scientists; they are organizing research communities and building patient registries; they are even selling cupcakes to start research centers. This short film celebrates eight of these stories -- and calls out the Chan Zuckerberg Initiative’s commitment to supporting patients and rare disease communities in their quest for cures.