Our world faces climate, economic, and sustainability challenges that we don’t yet have the tools to fix. The film “Driving Reactions” explores how directed evolution and the chemical sciences are creating some of these new tools. This is the fifth addition to the well-received Chemistry Shorts™ film series presented by the Camille and Henry Dreyfus Foundation. The series spotlights the positive impact of chemistry on modern life as scientists work to solve important problems and create new opportunities that benefit humanity. Featuring Hal Alper, University of Texas Austin, and Nobel Laureate Frances Arnold, Caltech